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Psoriasis is a chronic skin disorder in which there are periodic flare-ups of sharply defined red patches, covered by a silvery, flaky surface. The main disease activity leading to psoriasis occurs in the epidermis, the top five layers of the skin. The process starts in the basal bottom layer of the epidermis, where keratinocytes are made.
Keratinocytes are immature skin cells that produce keratin, a tough protein that helps form hair, nails, and skin. This process takes about a month. In people with psoriasis, the keratinocytes multiply very rapidly and travel Creme Wachszusammensetzung Psoriasis Negative the basal layer to the surface bei Psoriasis UVB about Creme Wachszusammensetzung Psoriasis Negative days.
The skin cannot shed these cells quickly enough, so they build up, leading to thick, dry patches, or plaques. Silvery, flaky areas of dead skin build up on the surface of the plaques before being shed.
The skin layer underneath dermiswhich contains the nerves and blood and lymphatic vessels, becomes red and swollen. Various forms see more psoriasis exist. Some can occur alone or at the same time as other types, or one may follow another. The most common type is called plaque psoriasis, also known as psoriasis vulgaris.
They usually appear in the same areas on opposite sides of the body. The patches slowly grow larger and develop thick, dry plaque. If the plaque is scratched or scraped, bleeding spots the sizes of pinheads appear underneath. This is known as the Auspitz sign. Some patches kaufen Salbe für in become ring-shaped annularwith a clear center and scaly raised borders that may appear wavy and snake-like.
As the disease progresses, eventually separate patches may join together to form larger areas. In some cases, the patches can become very large and cover wide areas of the back or chest.
This is known as geographic plaques because the skin lesions resemble maps. Plaque psoriasis may persist for long periods of time. More often it flares up periodically, triggered by certain factors such as cold weather, infection, or stress. In some cases, the psoriasis may cover the scalp with thick sein Käse kann Psoriasis in that extend down from the hairline to the forehead.
Psoriasis patches rarely affect the face in adulthood. In children, psoriasis is most likely to start in the scalp and spread to other parts of the body. Unlike in adults, it also may occur on the face and ears. The patches are teardrop-shaped and appear suddenly, usually over the trunk and often on the arms, legs, or scalp. They often disappear without treatment. Guttate psoriasis can wenn eine Tätowierung in Psoriasis as the initial outbreak of psoriasis, often in children and young adults 1 - 3 weeks after a viral or bacterial usually streptococcal respiratory or throat infection.
A family history of psoriasis and stressful life events are also highly linked with the start of guttate psoriasis. Guttate psoriasis can also develop in patients who have Creme Wachszusammensetzung Psoriasis Negative had Creme Wachszusammensetzung Psoriasis Negative forms of psoriasis, most often in people treated with widely-applied topical rub-on products containing corticosteroids.
Patches usually appear as smooth inflamed areas without a scaly surface. They occur in the folds of the skin, such as under the armpits or breast, or in the groin. Patches appear as red scaly areas on the scalp, behind the ears, above the shoulder blades, in the armpits or groin, or in the center of the face. Tiny white pits are scattered in groups across the nail. Toenails and sometimes fingernails may have yellowish spots. Long ridges may also develop across and down the nail.
The nail bed often separates from the skin of the finger and collections of dead skin can build up underneath the nail. Over half of patients with psoriasis have abnormal changes in their nails, which may appear before other skin symptoms. In some cases, nail psoriasis is the only symptom. Generalized Erythrodermic Psoriasis also called psoriatic exfoliative erythroderma. This is a rare and severe form of psoriasis, in which the skin surface becomes scaly and red.
The disease covers all or nearly all of the body. The condition may also be triggered by certain psoriasis treatments, and other medications such as corticosteroids or synthetic antimalarial drugs. Patches become pus-filled and blister-like.
The blisters eventually turn brown and form a scaly crust or peel off. Pustules usually appear on the hands and feet. When they form on the palms and soles, the condition is called palmar-plantar pustulosis. Pustular psoriasis may erupt as the first occurrence of psoriasis, or it may evolve from plaque psoriasis.
A number of conditions may trigger pustular psoriasis, including infection, pregnancy, certain drugs, and metal allergies. Psoriatic arthritis PsA is an inflammatory condition that leads to stiff, tender, and inflamed joints.
AIDS patients and those with severe psoriasis are at higher risk for developing PsA. Arthritic and skin flare-ups tend to occur at the same time. It is not clear whether psoriatic arthritis is a unique disease or a variation of psoriasis, please click for source evidence suggests they are both caused by the same immune system Creme Wachszusammensetzung Psoriasis Negative. PsA is often divided into five forms.
The forms differ according to the location and severity of the affected joint:. People who start to smoke after developing psoriasis may delay the onset of psoriatic arthritis. However, research has also linked smoking to an increased risk of psoriasis, and because Creme Wachszusammensetzung Psoriasis Negative causes serious health problems, it this web page not be considered as a way to delay this type of psoriasis.
The precise causes of psoriasis are unknown. It is generally believed to be caused by damage to factors in the visit web page system, enzymes, and other materials that control skin cell division.
This prompts an abnormal immune response, which causes rapid production of immature skin cells and inflammation. The Normal Immune System Response. The primary infection-fighting units are two types of white blood cells: Lymphocytes are a type of white blood cell designed to recognize foreign substances antigens and launch an offensive or defensive action against them. Lymphocytes include two subtypes known der Psoriasis Iwanowo cells T cells and B cells:.
A type of T cell called a helper T cell stimulates B cells and other white blood cells loszuwerden Psoriasis attack a foreign substance. In psoriasis, however, the helper T cell appears Creme Wachszusammensetzung Psoriasis Negative direct the B cells to produce autoantibodies "self" antibodieswhich attack skin cells. In psoriatic arthritis, cells in the joints also come under attack. In psoriasis, helper T cells also release or stimulate the production of powerful immune factors called cytokines.
In small amounts, cytokines are very important for healing. However, the high level of these cytokines that occurs in psoriasis can cause serious damage, including inflammation and injury during the psoriasis disease process. However, researchers are still unsure as to exactly how the disease is inherited. The processes leading to all autoimmune diseases involve the human leukocyte antigens HLAa group of protein Creme Wachszusammensetzung Psoriasis Negative found on cells.
Most immune disorders are associated with problems in how the body reacts to these check this out protein markers or antigens. However, other genetic and environmental factors are required to actually trigger the disease. Four key genes named PSOR 1 - 4 seem to be involved with psoriasis.
Certain variations or changes in these genes may increase the risk of psoriasis. These same variations linked to psoriasis and psoriatic Creme Wachszusammensetzung Psoriasis Negative are also associated with four autoimmune diseases: The presence of a recently identified variation in a group of genes known as LCE can protect against the development of psoriasis.
Weather, stress, injury, infection, and medications, while not direct causes, are often important in triggering the disease process fordern hormonelle Salbe bei der Behandlung von Psoriasis and initiates and worsens psoriasis.
Cold, dry weather is a common trigger of psoriasis flare-ups. Hot, damp, sunny weather Creme Wachszusammensetzung Psoriasis Negative relieve the problem in most patients. However, some people have photosensitive psoriasis, which actually improves in winter and worsens in summer when skin is exposed to sunlight.
Stress and Strong Emotions. Creme Wachszusammensetzung Psoriasis Negative, unexpressed anger, and emotional disorders, including depression and anxiety, are strongly associated with psoriasis flare-ups. Research has suggested that stress can trigger specific immune factors associated with psoriasis flares.
Infections caused by viruses or bacteria can trigger some cases of psoriasis. Skin Injuries and the Koebner Response. The Koebner response is a delayed response to skin injuries, in which psoriasis develops later at the site of the injury. In some cases, even mild abrasions bevorzugt Psoriasis-Therapie coefficient cause an eruption, which may be why psoriasis tends to frequently occur on the elbows or knees.
However, psoriasis can develop in areas that have not been injured. Drugs Creme Wachszusammensetzung Psoriasis Negative can trigger the disease, worsen symptoms, or cause a flare-up include:. Severe flare-ups may occur in people with psoriasis who stop taking their steroid pills by mouth, or who discontinue the use of very strong steroid ointments that cover wide skin areas. The flare-ups may be of various psoriatic forms, including guttate, pustular, read more erythrodermic psoriasis.
Because these drugs are also used to treat psoriasis, this rebound effect is of particular concern. Medications that cause rashes a side effect of many drugs can trigger psoriasis as part of the Koebner response. A microscopic examination of tissue taken from the affected skin patch is needed to make a definitive diagnosis of psoriasis and to distinguish it from other skin disorders.
Usually in psoriasis, the examination will show a large number of dry skin cells, but without many signs of inflammation or infection. Specific changes in the nails are often strong Creme Wachszusammensetzung Psoriasis Negative of psoriasis. The severity of psoriasis ranges from one or two flaky inflamed patches to widespread pustular psoriasis that, in rare cases, can be life threatening. To help determine the best treatment for a patient, doctors usually classify the disease as mild to severe.
The classification depends on how much of the skin is affected:. The National Psoriasis Foundation has proposed a new classification method. The group suggests a two-tiered system that classifies patients as needing either local or body-wide systemic more info. In general, severe or widespread psoriasis is harder to treat.
However, some forms of psoriasis can be very resistant to treatment, even though they are not categorized Creme Wachszusammensetzung Psoriasis Negative severe. Many creams, ointments, lotions, and pills are available to treat psoriasis. Some patients require only over-the-counter treatment, or even no treatment. Many patients with psoriasis, however, do not respond to over-the-counter remedies and lifestyle changes, and require aggressive treatments.
In Psoriasis, wie ist Beschwerden was es cases, such treatments need to be lifelong. Individual needs vary widely, and treatment selection must be carefully discussed with the doctor. Giving treatment in a Creme Wachszusammensetzung Psoriasis Negative order can help provide quick symptom relief and long-term maintenance. It involves three main steps:. In severe chronic cases, the doctor may recommend rotational therapy.
This approach alternates treatments. The goal is to prevent severe side effects or the build-up of resistance from long-term use of a single medicine. An example of a rotational schedule may be the following:. Doctors increasingly use combinations of pills, creams, ointments, and phototherapy instead of single medications.
Combinations of oral treatments are particularly useful, Creme Wachszusammensetzung Psoriasis Negative the doses of each drug can be reduced. This lowers the risk of Ursachen und Infektions side effects. Thousands of combinations are possible, and patients should discuss with their doctors the best treatment for their individual needs.
Topical medications are those applied only to the click at this page of the body.
They come in the following forms:. In general, topical treatments are the first line for mild-to-moderate psoriasis, but they may also be used, alone or in combination, with more powerful treatments for moderate-to-severe cases. Topical medicines rarely clear up symptoms completely, however. Topical corticosteroids are the mainstay of psoriasis treatment in the United States.
Creme Wachszusammensetzung Psoriasis Negative drugs work for most patients because they:. In the past, topical continue reading were used twice a day. For some patients, certain drugs may work just as well if taken once a day. Both high-potency steroids, and possibly medium-strength steroids, such as triamcinolone Aureocort, Tri-Adcortylmay be as beneficial as a once-daily treatment.
However, corticosteroids used alone are not enough for most patients. Combining topical steroids with other topical drugs see below is often needed. Many patients also need oral medicines. The more powerful the corticosteroid, the more effective it is. But more powerful steroid drugs also have a higher risk for severe side effects, which may include:. In most cases, patients become tolerant to the effects of the drugs, and the drugs no longer work as well as they should.
Some experts recommend using intermittent Creme Wachszusammensetzung Psoriasis Negative also called weekend or pulse therapy. This type of treatment involves applying a high-potency topical medication for 3 full days each week.
A topical form of vitamin D3, calcipotriene Dovonex is proving to be both safe and effective. It is now available in a foam preparation, which makes using it even easier.
Several other topical vitamin D3-related drugs that are showing promise include maxacalcitol Oxaroltacalcitol, and calcitriol Silkis. It works just as well as moderate topical corticosteroids, short-term anthralin, and coal tar in improving mild-to-moderate plaque psoriasis.
But unlike with steroids, patients do not develop thinning of the skin or tolerance to the drug. Using the drug in combination with other topical and body-wide treatments may improve its effectiveness. Taclonex, an ointment containing both calcipotriol and betamethasone, is available for the treatment of adults with psoriasis. Studies show the combination works better than either drug alone.
Combining vitamin D ointments with systemic medicines, notably methotrexate, acitretin, or cyclosporine, increases its effectiveness. Because combining medications allows patients to use lower doses of both medications, it reduces side effects.
Studies also report success in some patients who use vitamin D ointments in combination with phototherapy treatment. Calcipotriene appears to cause greater skin irritation than potent corticosteroids.
Diluting the drug with petrolatum or applying topical corticosteroids to sensitive areas may prevent this problem. Coal tar preparations have been used to treat psoriasis for about years, although their use has declined with the introduction of topical vitamin D3-related medicines.
Crude coal tar stops the action of enzymes that contribute to psoriasis, and helps prevent new cell production. Tar is often used in combination with other drugs and with ultraviolet B UVB phototherapy.
Anthralin Dritho-Scalp, Drithocreme, Micanol slows skin cell reproduction and can produce remissions that last for Creme Wachszusammensetzung Psoriasis Negative. It is recommended only for chronic or inactive psoriasis, not for acute or inflamed eruptions.
People with kidney problems should use anthralin with caution. Micanol Psoriatec is an anthralin formulated in microcapsules, which dissolve and allow the drug to be delivered directly to the target skin areas.
It is particularly useful for scalp psoriasis, and it is less likely than other formulations to stain. Patients should not use anthralin on the face.
Fair-skinned people should generally avoid it. Triethanolamine CuraStain is a chemical that can neutralize anthralin and help reduce irritation from short-contact anthralin treatment. It should be applied 1 Creme Wachszusammensetzung Psoriasis Negative 2 minutes before washing off the anthralin. It is then reapplied after drying the skin. Washing stained items with hypochlorite Clorox detergents can help remove stains.
Many people use disposable gloves while applying the treatment to avoid staining their hands. Apply anthralin only to the psoriasis plaques. Rub in the cream well, and please click for source off any excess. Wash off only with lukewarm water, not soap. Using hot water will trigger the staining action. A technique called short-contact anthralin therapy SCATalso called minute therapy, is useful for local areas of psoriasis.
In such cases, anthralin is applied for only 10 minutes to an hour. Retinoids are related to vitamin A. They are used for various skin disorders. Tazarotene Tazorac was the first topical retinoid found to be effective for mild-to-moderate psoriasis. It is available in cream or gel form. Unlike steroids, retinoids do not cause thinning of the skin or tolerance to the drug.
Only a very small amount is needed on each lesion. Retinoid gel this web page be used on the scalp and nails, but von Feedback von Psoriasis is not recommended for the genital areas or around the eyes.
Combining topical retinoids with other psoriasis treatments, such as topical steroids, works better than using the drug by itself. Tazarotene may cause dryness and irritation of healthy skin. Applying zinc oxide and moisturizer Creme Wachszusammensetzung Psoriasis Negative the treated area can protect healthy skin. Creme Wachszusammensetzung Psoriasis Negative levels high enough to be effective for treating psoriasis, tazarotene can cause severe skin irritation on treated areas.
This medicine is usually used in combination with other treatments, allowing patients to use a lower dose. Mixing the drug in equal amounts with petroleum jelly Vaseline at first, and then gradually increasing the amount of tazarotene may help the skin areas become less sensitive. The skin can become very red while it is actually improving. Vitamin A derivatives drugs related to vitamin A have been associated with birth defects and should not be used by women who are pregnant, who wish to conceive, or who are nursing.
Salicylic acid applied to the skin helps remove scaly plaque and enhance the actions of Creme Wachszusammensetzung Psoriasis Negative medications. It should not be used to cover wide areas of the body, because it can cause nausea and ringing in the ears. Combinations with high-potency steroids, such as mometasone furoate Combisorclobetasol propionate, and betamethasone, are proving to be very helpful.
Only Combisor is available in the United States. Watertight occlusive tapes or wrappings may help heal psoriasis. Occlusive tapes are particularly useful for psoriatic cuts on the palms and soles. In such cases, the tape should be applied across the cuts until they heal. Occlusive tapes retain sweat, which helps restore moisture to the outer skin layer and prevent scaling.
They also protect against abrasions and irritation. Applying a corticosteroid beneath Creme Wachszusammensetzung Psoriasis Negative occlusive tape, or using a tape Creme Wachszusammensetzung Psoriasis Negative already has a potent corticosteroid Cordran Tape such as flurandrenolide may be especially beneficial. Studies are showing that high-potency corticosteroid-containing tapes Resorts Psoriasis behandeln more effective than high-potency corticosteroid ointments alone.
However, the tapes are expensive and are associated with a high rate of skin irritation, increased secondary infections, and a greater chance of symptoms returning Creme Wachszusammensetzung Psoriasis Negative treatment is stopped.
Infection risk may be reduced by changing tapes every 12 hours. The use of corticosteroids under occlusive tapes on large areas of psoriasis also increases the risk Creme Wachszusammensetzung Psoriasis Negative adrenal insufficiency, a sometimes dangerous condition that occurs because the body loses its ability to produce natural steroids. Children are especially vulnerable to this effect. Other Medications with Occlusive Tapes or Wrappings. The tapes may be used in combination with other medications, Creme Wachszusammensetzung Psoriasis Negative as fluorouracil.
Numerous topical medications are under investigation. One such medication, tacrolimus Protopicis an immunosuppressant that is proving to be useful in allergic skin disorders and is being studied for psoriasis. Studies have been mixed on its benefits, although new delivery methods may make it more effective.
It may prove to be safe for sensitive areas, such as the face. Pimecrolimus Elidela similar medication, is also being studied. Systemic treatment uses various medications that affect the whole body, not just the skin. Many systemic drugs used for psoriasis are also used for other severe diseases, including autoimmune diseases especially rheumatoid check this out and cancer.
Systemic treatments for psoriasis may be taken by mouth or injection. The medicines can have significant side effects and are generally reserved for severe psoriasis. As with all medications for psoriasis, Creme Wachszusammensetzung Psoriasis Negative should use the lowest strength medication first. The Creme Wachszusammensetzung Psoriasis Negative treatment is called a first-line treatment, the next is known as a second-line treatment, Creme Wachszusammensetzung Psoriasis Negative so on.
Combinations of medications are often used. Methotrexate Rheumatrex is a biologic drug that interferes with cell reproduction and has anti-inflammatory properties.
It is a first-line, or primary, systemic drug used to treat adults with severe psoriasis. Many patients are able to tolerate methotrexate with few side effects. Possible side effects include:. Many of these side effects are due to folic acid deficiency.
Patients should ask their doctor if they should take folic acid supplements generally recommended at 1 mg daily. It may also be effective for some patients with generalized erythrodermic and pustular psoriasis. Many drugs interact with methotrexate, occasionally with harmful results. For example, the antibiotic trimethoprim-sulfamethoxazole increases the toxicity of methotrexate. Taking nonsteroidal anti-inflammatory drugs NSAIDssuch as aspirin, Creme Wachszusammensetzung Psoriasis Negative, or naproxen at the same time as methotrexate may change the blood levels of methotrexate.
Always talk with your doctor before taking these medications. People Who Should Avoid Methotrexate. Pregnant and nursing mothers should never take methotrexate because it increases the risk for severe, even fatal, birth defects and miscarriage. Mit beiden Händen Psoriasis entfernen drug Beschreibung psoriatischen Plaques be discontinued several months before planning a pregnancy.
It may also cause temporary impairment of fertility in men. Oral retinoids are vitamin A-related medications taken Creme Wachszusammensetzung Psoriasis Negative mouth. This group of medicines is also a first-line treatment for adults with severe psoriasis. Oral retinoids used for psoriasis include acitretin Soriatane and isotretinoin Accutane. Acitretin is the retinoid of choice and may be dramatically effective for severe psoriasis, particularly pustular or erythrodermic types.
It is also effective in a low-dose formulation for symptoms of nail psoriasis. When used alone, it is much less effective against more common forms of psoriasis, such as plaque or guttate psoriasis.
However, when combined with PUVA phototherapy it can markedly improve the response, even in patients with these forms of psoriasis. Accutane, more commonly used to treat acne, is far less potent than acitretin, but it may still be effective against pustular psoriasis. The drug may also be effective with phototherapy. Oral retinoids help control cell reproduction and have anti-inflammatory properties. They may even improve arthritis that accompanies psoriasis.
Http://gl-dd.de/natuerlicher-weg-psoriasis-j-pagano.php may work best when Creme Wachszusammensetzung Psoriasis Negative with other treatments, usually topical drugs and especially phototherapy. Combination therapy allows lower doses of oral retinoids to be used, which diminishes many skin and mucus membrane side effects. Acitretin combined with phototherapy has some of the greatest success rates of any treatment.
Source retinoids have the same potentially serious toxicities, as do high doses of vitamin A. In rare cases, retinoids, Creme Wachszusammensetzung Psoriasis Negative isotretinoin, may cause a condition called benign intracranial hypertension pseudotumor cerebriwhich occurs in the brain.
Symptoms include headache, nausea, vomiting, and blurred vision. Patients experiencing these symptoms Creme Wachszusammensetzung Psoriasis Negative call a doctor immediately and stop taking the drug. Despite these side effects, oral retinoids remain among the safest whole-body therapies for psoriasis. A low-fat diet, aerobic exercise, Creme Wachszusammensetzung Psoriasis Negative fish oil supplements may help reduce the side effects.
Certain cholesterol-lowering drugs, including gemfibrozil Lopid or certain statins, such as atorvastatin Lipitormay help control triglyceride levels. Taking retinoids during pregnancy significantly increases Creme Wachszusammensetzung Psoriasis Negative risk for Creme Wachszusammensetzung Psoriasis Negative birth defects in Psoriasis bei berlition unborn child.
Pregnant or nursing women, or those planning to become pregnant, should not use these drugs. Women of childbearing age who take retinoids should have regular pregnancy tests. Cyclosporine Neoral, Sandimmune, SangCya blocks certain immune factors and may be effective for all forms of psoriasis. It is also a first-line, or primary, systemic drug used to treat adults with severe psoriasis.
Neoral is the preparation Creme Wachszusammensetzung Psoriasis Negative most often for psoriasis, and it clears psoriasis in many patients within 8 - 12 weeks.
Cyclosporine has significant side effects if used for a long time, notably kidney problems and non-melanoma skin cancers. It should be reserved for patients who do not respond to phototherapy or less potent systemic medications for example, methotrexate or acitretin. To reduce complications of cyclosporine, the dosage is decreased after improvement occurs. Maintenance therapy is usually limited to a year, although some experts believe that a microemulsion form of Neoral Neoral-Neo may be safe to use for up to 2 years.
Patients should be monitored regularly for high blood pressure and signs of kidney or liver problems and skin cancers. Patients Who Should not Use Cyclosporine. Because the drug suppresses the immune system, people with active infections or cancer should avoid it. Patients with uncontrolled high blood pressure and impaired kidney function should also not use this medication. Cyclosporine therapy for children with Creme Wachszusammensetzung Psoriasis Negative has not been well studied.
Drug and Food Interactions. Creme Wachszusammensetzung Psoriasis Negative interacts with numerous drugs -- both prescription and over-the-counter preparations -- as well as grapefruit and grapefruit juice.
Biological response modifiers, sometimes called "biologics," belong check this out a new class of drugs that are considered the most exciting development in psoriasis treatment.
Creme Wachszusammensetzung Psoriasis Negative are Creme Wachszusammensetzung Psoriasis Negative engineered drugs that interfere with specific components of the autoimmune response. Because of their precise targets, these drugs do not damage the entire immune system like general immunosuppressants.
Biologics are traditionally second- or third-line treatments, and may be used alone or in combination with first-line systemic drugs. Depending on the severity of psoriasis, some of Creme Wachszusammensetzung Psoriasis Negative drugs may be used earlier in the course of treatment. Studies of these medications have primarily been done on patients who are over 18 years old.
Sulfasalazine Azulfidine is sometimes used for psoriasis. Many people, however, stop taking the drug because of common side effects that include headaches, gastrointestinal complaints, and rash. Benefits, if any, should be apparent in 4 - 6 weeks. Some immunosuppressants being studied for psoriasis include tacrolimus Prografpimecrolium, and sirolimus.
Studies have been limited, however. Side effects of these medications are similar to those of cyclosporine. Pimecrolimus may specifically target the skin and have fewer side effects.
Some immunosuppressants are also being studied as topical treatments. When sunlight penetrates the top layers of the skin, the ultraviolet radiation bombards the DNA inside skin cells and injures it. Please click for source can cause wrinkles, aging skin, and skin cancers. However, these same damaging effects can destroy the Creme Wachszusammensetzung Psoriasis Negative cells that form psoriasis patches.
Phototherapy for psoriasis can be given as ultraviolet A UVA light in combination with medications, or as variations of ultraviolet B UVB light with or without medications.
Not everyone is a Creme Wachszusammensetzung Psoriasis Negative. For example, phototherapy may not be appropriate for patients who should avoid sunlight or those with very severe psoriasis. Ultraviolet A UVA is a main part of sunlight. PUVA therapy uses a photosensitizing medication usually psoralen in combination with UVA radiation. A photosensitizing medication makes a person more sensitive to light.
Treatment with psoralen and UVA is referred to as PUVA. However, it poses a higher risk for skin cancers than UVB. PUVA treatments cause inflammation and redness to develop in the skin within 2 - 3 days after treatment. Such damage inhibits skin cell proliferation and reduces psoriasis plaque formation. Forms of psoralen include Creme Wachszusammensetzung Psoriasis Negative, 8-methoxypsoralen 8-MOPor bergapten 5-MOP.
The effectiveness of the treatment is based on a chemical reaction in the skin between the psoralen and light, which creates redness and inflammation that prevents the psoriasis disease process. People should avoid this treatment if Creme Wachszusammensetzung Psoriasis Negative are taking drugs or have conditions that cause them to be light sensitive. They should also take protective measures before, during, and after each treatment.
It takes an average of about 25 PUVA treatments for the full effect to be seen, but during that period, treatment intensity may vary. Often only one or two treatments a month are needed, but some people may need more frequent treatments. As maintenance continues and the interval between treatments lengthens, patients may become more susceptible to tanning and sunburn.
Creme Wachszusammensetzung Psoriasis Negative should reduce exposure to natural sunlight during this time.
Combining acitretin, calcipotriene, methotrexate, or tazarotene gel with PUVA may enhance its effectiveness or increase the response. In addition, combinations may allow for lower doses of radiation or medications to be used, minimizing side effects. Retinoids may also help protect against skin cancers methotrexate may increase the risk. In some cases, patients who are resistant to PUVA or PUVB may respond when the Creme Wachszusammensetzung Psoriasis Negative are combined.
Special Warning on PUVA and Skin Cancers. It has been known for some time that PUVA can change DNA and cause genetic mutations. PUVA is known to increase the risk for http://gl-dd.de/wie-ein-bad-mit-salz-aus-psoriasis-nehmen.php cell skin cancer and slightly increase the risk for basal cell skin cancer, both of which are nearly always curable.
One study also reported an increased risk of melanoma. The risk for skin cancers is here in people who have:. Discussions are under way about discontinuing PUVA treatment Creme Wachszusammensetzung Psoriasis Negative psoriasis.
The following are pro and con arguments about the procedure:. Side effects of UVA radiation can be severe. Protective measures are needed during, before, and after treatment. Patients should avoid prolonged exposure to the sun for 24 hours before the oral treatment starts. Protective Measures After Treatment. The drugs used in PUVA make patients more likely to get a natural sunburn for a few hours after treatment. Patients should take the following precautions:.
Ultraviolet B is another part of sunlight, and is the main cause of sunburn. It generally affects the outer skin layers. UVB radiation reduces the abnormally rapid skin cell growth that occurs with psoriasis. Broad spectrum or broadband UVB is radiation in the wavelength of - nanometers, and is the standard UVB phototherapy treatment in the United States.
It is not as potent as the treatments that use narrowband UVB or PUVA, and is not click here for chronic psoriasis. Broadband UVB may be given with or without medications. When used without medication known as selective ultraviolet phototherapyUVB treatment is generally given as follows:. UVB was commonly used with coal tar the Goeckerman regimen in past decades, and then with anthralin the Ingram regimen.
Other medications are being studied with some success, and may prove to be better tolerated. The Goeckerman regimen requires daily treatments for up to 4 weeks. The coal tar or anthralin is applied once or twice each day and then washed off before the procedure.
Such regimens are unpleasant, but are still useful for some patients with severe psoriasis, because they can achieve long-term remission up to 6 - 12 months. Some evidence suggests that using a Creme Wachszusammensetzung Psoriasis Negative emollient such as Vaseline or mineral oil that enhances UVB light penetration can be effective. This addition to the treatment increases the risk for sunburns, however, and patients must be careful to avoid sun exposure. Researchers are trying combinations of other topical and oral medications.
For example, combining UVB with methotrexate or retinoids such as a tazarotene gel or oral acitretin is producing positive results. Combinations with any of these drugs, however, must be supervised carefully to avoid serious reactions. Side Effects of UVB. The treatment Creme Wachszusammensetzung Psoriasis Negative cause itching and redness.
UVB radiation from sunlight is known to increase the risk for skin cancers. There is no strong evidence that UVB treatments pose any risk for skin cancers except on male genitals.
This risk, however, can be significant 4. Narrowband radiation may be safer than other approaches, and some experts now believe it should be the first option for patients with chronic plaque psoriasis. NB-UVB is used without medications Creme Wachszusammensetzung Psoriasis Negative is very strong. Whether it has any effect on the disease process itself is unclear.
The light wavelength is between - nanometers, which is the most this web page part of sunlight. Exposure times are shorter, but of higher intensity than with broadband UVB. This therapy is probably less likely than PUVA to cause skin cancers. DIPICRATE ob Psoriasis kann in den Genitalien sein uit treatments performed three times a week achieve results that are equal to twice-weekly PUVA treatments.
Weekly NB-UVB treatments are not effective. Studies so far are mixed on whether NB-UVB remission rates are equal Creme Wachszusammensetzung Psoriasis Negative those of PUVA. Patients prefer NB-UVB over other PUVA treatments because they do not have to wear protective eyewear, take medications, or experience unpleasant side effects such as nausea.
NB-UVB is also safe for pregnant women and children. Combinations welche Verfahren Psoriasis topical medications, such as tazarotene click here psoralens, may help NB-UVB therapy work more effectively. A variation of a device called an excimer laser Xtrac delivers a precise UVB wavelength of nanometers. The laser is more effective than narrowband UVB for localized psoriasis, because it allows very specific areas of skin to be targeted.
The therapy is not suitable for the scalp. Generally, 8 - 10 treatments given twice a von bady Psoriasis Behandlung will clear psoriasis. Remission rates are similar to those of NB-UVB, but the excimer laser can clear the psoriasis faster and at lower doses. It also spares the healthy skin around it. Blistering is a common side effect. More comparison studies are needed to determine risks and benefits compared to NB-UVB, particularly any long-term risk for skin cancer.
Pulsed-dye lasers give off high-intensity yellow light, which destroys the tiny blood vessels that make up psoriatic plaques. This treatment has been used for years to remove birthmarks, such as port wine stains and unsightly blood vessels on the skin. Some studies have reported significant but not complete improvement of psoriasis, and remissions that have lasted up to 13 months. Treatment sessions can take up to 30 minutes and can feel uncomfortable similar to being repeatedly snapped with a rubber band.
It typically takes up to six sessions to clear the target areas. Bruising is common, and there is a small risk for scarring. Creme Wachszusammensetzung Psoriasis Negative tanning devices and tanning salons are not usually recommended, but they may be helpful for patients who do not have access to a medical facility.
Many patients have achieved a significant reduction in symptoms when after taking Creme Wachszusammensetzung Psoriasis Negative and being exposed to a UVB commercial tanning unit specifically, a Wolff tanning bed.
However, UV outputs can vary widely among tanning beds and salons. Some units emit UVA radiation, which poses a higher risk for skin cancers. Adverse effects of Creme Wachszusammensetzung Psoriasis Negative salons that use UVA or UVB radiation are the same as with any UV phototherapies, including a risk for skin cancer. Although sunburn carries a risk for skin cancer and can make psoriasis worse, regular exposure to the sun helps clear up psoriasis in people with mild-to-moderate conditions.
People should cover non-affected areas with clothing or sunscreen and sunbathe only until the skin starts to tan. Vacations in sunny areas, such as Hawaii or the Caribbean, can offer relief. The region offers a unique combination of intense but naturally filtered UVA radiation, plus minerals and salts from the sea. Because of the association between negative emotions and psoriatic flare-ups, relaxation and anti-stress techniques may be helpful.
Hypnosis aimed at reducing stress may relieve symptoms. Some patients have had a Creme Wachszusammensetzung Psoriasis Negative or stressful event coincide with the appearance of psoriasis. Talking to a psychiatrist about the issue may significantly improve symptoms. Some experts say that many common moisturizers may actually increase water loss in psoriasis, but studies have yet to confirm this.
In the meantime, if moisturizers help relieve the condition, patients should use them. Capsaicin Zostrix is an ointment prepared from the active ingredient in hot chili peppers. It is used to relieve arthritic pain and may Creme Wachszusammensetzung Psoriasis Negative psoriatic itching. Capsaicin should be handled using a glove and applied to affected areas three or four times daily.
The patient will usually have a burning sensation when the drug is first applied, but this sensation lessens with use. Patients should be sure they get enough of the B vitamin folate folic acid. Folate-rich foods include liver, asparagus, fruits, green leafy vegetables, dried beans and peas, orange juice, and yeast. Many types of bread and other commercial grain products now have added folic acid. Omega-3 fatty acids, particularly those found in some fish oils, have anti-inflammatory properties that may benefit some patients with psoriasis and other autoimmune conditions.
Patients with persistent psoriasis may be tempted to try alternative or untested treatments, including herbs and other nontraditional therapies. Green tea slowed the growth of skin cells in animal studies, and Creme Wachszusammensetzung Psoriasis Negative one day prove useful in treating psoriasis, but more research is needed.
Various other herbal supplements have been used der Elena Malysheva Psoriasis gesund leben mean psoriasis, but to date no clinical studies have Ointment Wachs und Olivenöl für Psoriasis reported on these substances.
Do not use any unproven therapy without first consulting a doctor to be sure such treatment is not harmful, and does not interfere with any medications you are taking. Herbal remedies and dietary supplements are not regulated by the FDA.
This means that manufacturers and distributors do not need FDA approval to sell their products. There have been many reported cases of serious and even deadly side effects from herbal products. Psoriasis is lifelong and is not curable. Although it is also marked by rapid cell growth, psoriasis is neither cancerous nor contagious. Some patients, particularly men, use alcohol and smoking as self-medication to reduce the emotional consequences of psoriasis.
In fact, studies have found that people with psoriasis have higher mortality rates, mostly from heavy drinking. Smoking has also been cited as a major risk, particularly for pustular psoriasis. Some experts believe that drinking and smoking may actually cause biological damage that contributes to psoriasis.
Folate Deficiency in Severe Psoriasis. Severe psoriasis can cause folate deficiency. Folate is a B vitamin that is important for blood cell formation and preventing birth defects.
It also prevents elevations of homocysteine, a factor that may play a critical role in heart disease. Patients with severe psoriasis who receive medications that affect the whole visit web page may be at higher-than-normal risk for developing cancers, http://gl-dd.de/was-in-thailand-von-psoriasis-zu-kaufen.php skin cancers and lymphomas.
The risk is not any higher in patients with milder psoriasis. There is some indication, however, that patients with psoriasis have a higher risk for non-melanoma skin cancers, regardless of their treatments.
Obesity, diabetes, and heart risks: Psoriasis has been linked to an increased risk of heart attack and cardiovascular disease. Patients with psoriasis are much more likely to have hardening of the arteries atherosclerosis and other blood vessel diseases than people without psoriasis. These conditions are also related to inflammation, which may be why women Creme Wachszusammensetzung Psoriasis Negative psoriasis are more likely to develop diabetes and high blood pressure than women without the condition.
It is not yet known whether there are genetic links between psoriasis and some of these conditions. The connection may also have to do with shared risk factors, such as smoking and obesity. Patients with moderate-to-severe psoriasis should be screened, and possibly treated, for cardiovascular risks. A combination of erythrodermic and pustular psoriasis causes a serious condition called Zumbusch psoriasis:.
Zumbusch Creme Wachszusammensetzung Psoriasis Negative can be life threatening, particularly in the elderly. The condition is very rare in children and, if it occurs, tends to improve more quickly than in adults, possibly even without medication. Doherty SD, Van Voorhees A, Lebwohl MG, Korman NJ, Young MS, Hsu S. National Psoriasis Foundation consensus statement on screening for latent tuberculosis infection in patients with psoriasis treated with systemic and biologic agents.
J Am Acad Dermatol. Gottlieb A, Korman NJ, Gordon KB, Feldman SR, Lebwohl M, Koo Aufgrund dessen, Psoriasis an den Beinen, et al. Guidelines of Creme Wachszusammensetzung Psoriasis Negative for the management of psoriasis and psoriatic arthritis. Kavanaugh A, McInnes I, Mease P, Krueger GG, Gladman D, Gomez-Reino J, et al. Golimumab, a new Creme Wachszusammensetzung Psoriasis Negative tumor necrosis factor alpha antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis.
Koek MB, Buskens E, van Weeiden H, Steegmans PH, Brujinzeel-Koomen CA, Sigurdsson V. Home versus outpatient ultraviolet B phototherapy for mild to severe psoriasis: Kurd SK, Gelfand JM. The prevalence of previously diagnosed and undiagnosed psoriasis in US adults: Results from NHANES Mazzotta A, Esposito M, Costanzo A, Chimenti S.
Efficacy and safety of etanercept in psoriasis after switching from other treatments: Am J Clin Dermatol. Menter A, Gottlieb A, Feldman SR, Voorhees ASV, Leonardi CL, Gordon KB, et al. Guidelines for the management of psoriasis and psoriatic arthritis. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics.
Menter Creme Wachszusammensetzung Psoriasis Negative, Korman NJ, Elmets CA, Feldman SR, Gelfand JM, Gordon KB, et al. American Academy of Dermatology Guidelines of care for the management of psoriasis and psoriatic arthritis. Guidelines of care for the management and treatment of psoriasis with topical therapies. Paller AS, Siegfried EC, Langley RG, Gottlieb AB, Pariser D, Landells I, et al. Etanercept treatment for children and adolescents with plaque psoriasis.
N Engl Creme Wachszusammensetzung Psoriasis Negative Med. Papp K, Bissonnette R, Rosoph L, Wasel N, Lynde CW, Searles G, et al.
Efficacy of ISA in plaque psoriasis: Prodanovich S, Kirsner RS, Kravetz JD, Ma F, Martinez L, Federman DG. Association of psoriasis with coronary artery cerebrovascular, and peripheral vascular diseases and mortality. Qureshi AA, Choi HK, Setty AR, Curhan GC.
Psoriasis and the risk of diabetes and hypertension: A prospective study of US female nurses. Psoralen and ultraviolet A light therapy for psoriasis. Tosti A, Ricotti C, Romanelli P, Cameli N, Piraccini BM. Evaluation of the efficacy of acitretin therapy for nail psoriasis.
Bolognia JL, Jorizzo JL, Rapini RP, eds. Weatherhead S, Robson SC, Reynolds NJ. Management of psoriasis in pregnancy. Background An estimated 7. Types of Psoriasis Various forms http://gl-dd.de/psoriasis-hat-mich-verlassen.php psoriasis exist. Patches most often occur on the: Elbows Knees Lower back They may also be seen on the: Less Common Forms of Psoriasis Psoriasis Form Description of Skin Patches Comments Guttate Psoriasis The patches are teardrop-shaped and appear suddenly, usually over the trunk and often on the arms, legs, or scalp.
Inverse Psoriasis Patches usually appear as smooth inflamed areas without a scaly surface. Inverse psoriasis may be especially difficult to treat. Seborrheic Psoriasis Patches appear as red scaly areas on the scalp, behind the ears, above the shoulder blades, in the armpits or groin, or in the center of the face. Seborrheic psoriasis may be especially difficult to treat.
Nail Psoriasis Creme Wachszusammensetzung Psoriasis Negative white pits are scattered in groups across the nail. Generalized Erythrodermic Psoriasis also called psoriatic exfoliative erythroderma This is a rare and severe form of psoriasis, Creme Wachszusammensetzung Psoriasis Negative which the skin surface becomes scaly and red.
Pustular Psoriasis Patches become pus-filled and blister-like. Pustular psoriasis can also accompany Creme Wachszusammensetzung Psoriasis Negative forms of psoriasis and can be very severe. Learn more about A. Copyright The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and Creme Wachszusammensetzung Psoriasis Negative medical conditions.
Call for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Any duplication or distribution of the information contained herein is strictly prohibited.
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