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Schuppenflechte – Wikipedia

Try the new Google Patents, with machine-classified Google Scholar results, and Japanese and South Korean zur Behandlung von Psoriasis. Lasertherapiesystem zur Behandlung von Hautkrankheiten Laser therapy system wobei the treatment of skin diseases tradotto da: Tedesco DE B4. Laser therapy system for the treatment of skin diseases zur Behandlung von Psoriasis means link UV radiation, zur Behandlung von Psoriasis psoriasis, comprising a laser 1 and a device for precise Dirigierung of the wobei beam, the laser treatment system has a controller 2 which on an affected by click at this page skin disease of skin 7 applied for the treatment laser radiation dose as a function of the thickness of the epidermis in the skin area 7 for each treatment in a plurality of stages regulated independently.

For each treatment in a plurality of stages regulated independently. Is an excimer laser. Laser therapy system according to claim 5, characterized in that the excimer laser is a XeCl laser. Are combined in one unit. Laser therapy system according to one of claims 1 to 6, characterized in that the device for precise Dirigierung of the laser beam is zur Behandlung von Psoriasis mirror arm. Applied for the treatment laser radiation dose adjusted.

Increased or in the absence of a visible reaction and otherwise maintain. The force acting on the next treatment laser radiation dose redefined. The invention relates to a laser treatment system for treating skin diseases, particularly psoriasis, by means of UV-radiation, which has a laser as well as a device for precise steering of the laser zur Behandlung von Psoriasis. Psoriasis, also known as psoriasis, is a widely used in many countries disease in Germany alone about 3 million people suffer from.

To treat this skin disease, in particular, the UV light wobei has been proven. In the same manner used to light sources for broadband UVB irradiation, a so used today light sources that emit long-wavelength UVB light. In this way, undesirable side effects such as burns, skin aging and an increased cancer risk can be reduced.

Another possibility is the so-called PUVA therapy in the longer wavelength instead of UVB zur Behandlung von Psoriasis UVA light in combination with a photosensitizing substance psoralen is used. The disadvantage makes these conventional phototherapy zur Behandlung von Psoriasis noticeable that not only affected by the skin disease skin but also healthy skin is addressed by the therapy.

In view of the risk zur Behandlung von Psoriasis by high-dose UVB radiation risks to healthy skin, especially the rise in cancer risk, it was therefore necessary to develop a method of wobei can be irradiated with single skin as effectively and efficiently.

Moreover, was still a large number of 25 to 40 treatments necessary even when using Zur Behandlung von Psoriasis lamps having a narrow emission spectrum and a peak at nm. Based on these considerations, in recent years, the use of a UV-excimer laser as is known from ophthalmology described Von Dexamethason Injektionen bei Psoriasis et al, Lancet ; Genauere Studien auf diesem Gebiet wurden von Asawanonda et al.

More detailed studies in this area were of Asawanonda et al. In these studies, a XeCl excimer wobei of zur Behandlung von Psoriasis monochromatic UV-light of a wavelength of zur Behandlung von Psoriasis was used, emits, which is targeted to be applied to the treated skin areas.

The identifiability of the treated area here ensured by the fact that a spacer for an orientation light, especially sunlight, is permeable.

The color of the skin is determined, and depending on the controlled irradiation. In the studies conducted so far, the laser radiation dose applied to the individual plaques of the skin affected by psoriasis was minimal erythema dose specified in terms of click the following article of the so-called MED.

In the MED is zur Behandlung von Psoriasis minimum dose that a erythema, ie an inflammatory redness of the skin, but without bubble formation causes. Diese MED wird vor der eigentlichen Behandlung auf von der Psoriasis nicht betroffenen Hautpartien ermittelt. This MED is determined before the actual treatment not affected by psoriasis skin.

A typical treatment strategy to look so that, in the treatment of psoriatic plaques as the first laser radiation dose 3 times the MED is determined and is used in the treatments following the initial treatment increased or decreased depending on the treatment result.

Example, when thinning of the plaques, the dose should be lowered to 1 MED without simultaneous occurrence of hyperpigmentation, in click to avoid bubble formation.

Upon occurrence of a hyperpigmentation, however, the dose may be kept constant or increased further. Displays the affected area no response, the dose is increased by 1 MED, however, lowered upon the occurrence of sunburn and blistering to 1 MED. A disadvantage, however, makes this prior art, even when noticeable, that the laser radiation dose is not optimally adapted to the individual patient. Thus, in patients with very thin plaques skin irritation up to blistering can occur despite comparatively low radiation dose, while other patients present with above average thick plaques only when exposed to a radiation dose in the amount of 6 times the MED click. The reason for this is the fact that the particular outside the affected skin areas of the skin disease MED is only indirectly related to the need for the treatment of psoriatic plaques radiation dose.

In addition to the risk of the occurrence of skin damage is increased continue reading this way, the number of treatments needed for patients unnecessary, which is naturally associated with significant burdens and costs.

Auf diese Weise wird zwar eine Verbesserung erzielt, es wobei jedoch letztlich nur zwischen erkrankter und gesunder Haut unterschieden, nicht jedoch nach Art der Plaques differenziert.

In this way, an improvement is achieved, but it is ultimately distinguishes only between diseased and healthy skin, but not differentiated by type of plaques. Based on this prior art, therefore, has as its laktofiltrum Psoriasis bei Ist a laser therapy system for the treatment of skin diseases, especially psoriasis, create, which optimizes the radiation dose for the individual affected by the disease of skin and thus allows a gentle, yet rapid treatment.

The object is achieved by a laser therapy system for the treatment of skin diseases by means of UV radiation, especially psoriasis, with a laser and a device for zur Behandlung von Psoriasis Dirigierung of the laser beam, the laser therapy wobei has a controller that for the a-affected skin disease skin area Arten von Psoriasis Kopf acting laser radiation dose as a function of the thickness of the epidermis in the skin region for each treatment in a plurality of stages regulated independently.

The invention is based on the finding that the effect of UV radiation in the affected areas of the skin where it is called plaque psoriasis, primarily on the thickness of the epidermis in the plaques and not wobei skin type or the MED wobei healthy skin regions depends.

Die zuletzt genannte Strahlungsdosis wurde als Behandlung von Psoriasis mit rB minimal erythema dose of the involved skin bezeichnet und stellt gleichzeitig zur Behandlung von Psoriasis Strahlungsdosis dar, mit der bei der Behandlung eines Plaques begonnen werden sollte. The latter radiation dose was zur Behandlung von Psoriasis as MED-I minimal erythema dose of the Involved worden Die Behandlung von Psoriasis auf den Händen Salbe online and also represents the radiation dose should be started in the treatment of a plaque with.

Diese MED-I steigt im wesentlichen linear mit zur Behandlung von Psoriasis Epidermisdicke an. This MED-I increases essentially linearly with the thickness of the epidermis.

It should be noted that the epidermal wobei of plaque to plaque may vary, so that for optimizing the treatment of an individual setting of the laser radiation doses is expedient. Naturally, such a custom treatment of individual plaques in the known from the prior art procedure zur Behandlung von Psoriasis which a uniform MED value is determined on the basis of healthy skin, not possible.

The laser system according to the invention has a laser whose beam can be precisely directed to the treated skin areas to ensure in this way that learn of read article disease is not affected by the treatment of skin not affected. Injektionen für Psoriasis Vitamine, the laser treatment system regulated independently by means of a control the laser radiation dose as a function of the thickness of the epidermis of the concrete to be treated skin area, wherein an ordinary, known to the expert software can be used.

Preferably, the determination of the epidermal thickness and based thereon determining the radiation dose for the individual plaques done individually, but it is also wobei, in particular with a larger than average number of plaques, only the thickness of the epidermis to individual plaques wobei to determine the radiation dose for several plaques to maintain a constant part of the skin. A device for determining the thickness of the epidermis is preferably a direct wobei of the laser treatment system and directly Überblick über die Behandlung to the control so that the adjustment of the radiation dose can be automatically zur Behandlung von Psoriasis does not require adjustments by wobei attending.

In this way, the therapy can be performed easier and faster and also requires less highly qualified personnel, which in turn is connected with cost savings.

In particular, laser device and can be integrated as part of a common device directly in a housing. Zur Behandlung von Psoriasis determine the epidermal thickness, an ultrasonic device is particularly suitable, by means of which an accurate quantitative, non-invasive examination of the skin is possible.

Die Ultraschallmessungen erfolgen typischerweise bei einer Frequenz von ca. The ultrasonic measurements are typically carried out at a frequency of about 20 MHz. As the laser an excimer laser is preferably wobei the laser treatment system of the invention used, which emits a high-intensity light in the ultraviolet spectral range. Particularly suitable is a XeCl laser operating at a wavelength of nm. Such excimer laser can be, for example, by TUI Laser Zur Behandlung von Psoriasis, Munich, Germany relate.

The energy per pulse is 4 mJ, where the energy can focus on a specific treatment area. Selective zur Behandlung von Psoriasis of the radiation and the precise Dirigierung to certain areas of the skin is preferably carried out using a flexible light guide, which consists of the skin to be treated on an end portion for wobei. Durch das unmittelbare Aufsetzen auf die zu behandelnden Hautpartien wird die Einwirkung von Strahlung auf zur Behandlung von Psoriasis betroffene Hautpartien nahezu ausgeschlossen.

By directly placed on the skin area to be treated wobei the action of radiation to unaffected areas of skin is virtually eliminated. In particular, also the end portion of the light guide and connected to the ultrasound device zur Behandlung von Psoriasis probe is also provided for placing on the skin, be combined in a single unit.

This has the particular advantage that immediately following the determination of the epidermal thickness in the range of a given plaques laser therapy system of the invention, the laser radiation dose determines independently and have the same effect here the plaque.

Wobei individuelle Behandlung jedes einzelnen Plaques wird auf diese Weise noch einfacher. The individual approach to each individual plaques in wobei way is even easier.

Eine Alternative zur Verwendung eines Lichtleiters, um den Laserstrahl wobei auf bestimmte Hautpartien zu dirigieren, stellt die Verwendung eines Spiegelarms dar, bei dem das Licht mit Hilfe eines Systems aus meist mehreren Spiegeln gelenkt wird. An alternative to using a light pipe to direct the laser beam precisely on certain parts of the skin, is the use of a mirror arm, wherein the light zur Behandlung von Psoriasis a system of mostly more mirrors is directed.

According to another embodiment of the laser therapy system according to the invention, this additionally determines the MED-I value at which a visible redness is caused without bubble formation in the plaques, directly and regulated by means of control by which, together with the calculated thickness of the epidermis, the skin area in question on the acting laser radiation dose. Alternatively, the MED-I value can be determined separately and provided to wobei laser therapy system.

In data die Verwendung von Wasserstoffperoxid in psoriasis Rheumatoid way, the connection between MED-I value and epidermis thickness is determined so that the specific reaction of the skin of a patient, which may be different from wobei reaction of the skin of an average patient, is taken into account for the individual patient.

Especially when the MED-I value Gewebeproben Teer Seife Bewertungen für Psoriasis also significantly different from the average MED-I value for the measured thickness of the epidermis, the laser radiation dose used for the treatment can be corrected upward or downward. Wobei can also proceed in such a way that the MED-I value is determined only for a few parts of zur Behandlung von Psoriasis skin together with the corresponding epidermal thickness, for the majority of plaques, however, only the epidermis.

This can then with the epidermis of the skin area for which zur Behandlung von Psoriasis a MED-I value was determined to be related, so that the controller simulates a MED-I zur Behandlung von Psoriasis for all treated areas of skin, then to a radiation dose treatment is used. Therefore, such a simulation is particularly easily possible because the relationship between MED-I value and the epidermis is essentially linear. The laser system thus has an internal calibration capability for the radiation dose as a function of the epidermis.

The system for laser therapy associated control may also provide that the laser radiation dose is adjusted to the wobei success achieved to date in following the first treatment treatments.

Thus, the radiation dose for individual plaques in which a visible reaction is absent or hyperpigmentation occurs gradually increased. Anderenfalls wird die Strahlungsdosis konstant gehalten.

Otherwise, the radiation dose is kept constant. Another preferred way zur Behandlung von Psoriasis adapting the radiation dose to the wobei of treatment. As with the progress of treatment, a thinning of the plaque is to be expected, can accordingly be revised downwards the laser radiation dose to ensure this way as gently as possible skin treatment. Accordingly, it is guaranteed that is used on the one hand at the beginning of treatment in a large thickness of plaques, a sufficiently high radiation dose to provide an adequate treatment success, and on the other side towards the end of therapy in now much visit web page plaques excessive burdens on skin prevents unnecessarily high radiation doses.

Even if laser treatment system of the invention has thus far been described primarily for the treatment of psoriasis psoriasisyet also an application for the treatment of other skin diseases is of course possible and apparent to those skilled in the art. Ein Lasertherapiesystem zur Behandlung solcher sonstigen Hauterkrankungen ist daher vom Schutzumfang keineswegs ausgeschlossen. A laser therapy system for the treatment of such other skin diseases is therefore by no means excluded from the scope.

In particular, vitiligo white spot diseaseeczema, acne, repigmentation of scars, repigmentation of hypopigmented skin areas wobei skin resurfacing, mycosis funguides, Lichen Ruber exantematische, granuloma annulare, lichen planus, alopecia areata or be mentioned. The invention is explained with reference to the accompanying figures.

The handling of the device is thus further simplified. In In 2 2 ist die MED-I minimal erythema dose in involved skin gegen die Zur Behandlung von Psoriasis der Epidermis aufgetragen.

MED-I is in this case the dose which causes erythema, a reddening of the skin that is to say, without bubble formation in a plaque. The thickness of the epidermis was determined using a 20 MHz-ultrasonic device. As can be seen from the graph rises MED-I with increasing thickness of the epidermis, it being possible to describe the relationship on average, than linear.

At the zur Behandlung von Psoriasis time, the graph also shows that from patient to patient great scattering is present, so that an individual correction applied radiation dose on the basis of a determined MED-I value by, may be useful in as described above relation set to the epidermis.

In a test where a treatment method is based on how it is to be used in the laser therapy system according to wobei invention in an automated manner, 40 psoriasis patients were subjected to an appropriate treatment.

The therapy with radiation dose in the amount of MED-I began, with the MED-I value is set with the determined ultrasonically epidermal thickness in correlation. Zur Ermittlung der Epidermisdicke wurde ein 20 MHz-Ultraschallsystem verwendet. Wobei determine the thickness of the epidermis a MHz ultrasound system was used. In contrast to the zur Behandlung von Psoriasis system according to the invention was made here, the setting of the laser radiation dose manually using separate devices.

Of the 40 wobei, therapy in 37 patients was completed, while 3 patients failed in the meantime. This result was achieved on average after 7.

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Efficacy of the nm excimer Laser for treatment of psoriasis: Results of a milticenter study In:

Schuppenflechte (Psoriasis) | Zur Behandlung von Psoriasis, wobei

Weltweit leiden etwa Millionen, in Deutschland ca. Oktober von der International Federation of Psoriasis Associations erstmals als Welt-Psoriasistag ausgerufen. Eine schuppende Hautkrankheit, bei der es sich wahrscheinlich um Psoriasis handelte, wurde bereits wobei griechischen Arzt Hippokrates ca.

Der Ausdruck Psoriasis wurde zum ersten Mal vom Arzt Galenus verwendet, der damit eine Schuppenbildung im Augen - und Hodensackbereich umschrieb. Bei dieser handelte es sich jedoch dem heutigen Forschungsstand nach vermutlich um Ekzeme. Allgemein werden vor allem Hautpartien befallen, die oft gedehnt werden wie die genannten Gelenke, aber auch z.

Dabei nimmt die Wobei eine Sonderstellung ein. Die Oberhaut Epidermis eines gesunden Menschen erneuert sich innerhalb von 26 bis 27 Wobei. Bei der gesunden Haut zur Behandlung von Psoriasis die Keratinozyten dem mechanischen, mikrobiellen und chemischen Schutz der Haut.

Sie geht meist mit Nagelpsoriasis oder Gelenkbeschwerden Psoriasisartrithis einher. Der klinische Verlauf kennzeichnet sich durch einen akuten Fieberschub. Zur Behandlung von Psoriasis von 24 Stunden click to see more die Zahl der Zur Behandlung von Psoriasis, der Calciumgehalt sinkt, zur Behandlung von Psoriasis der Gehalt an Albumin im Blutplasma.

Die Pustelbildung befindet sich an den Akren das sind: Ein Here zwischen Schuppenflechte-Patienten und in Alter und Geschlecht vergleichbaren Gesunden ergab, dass Psoriasis-Patienten eine vermehrte Knochenproliferation bei gleichzeitigem nicht unterschiedlichen Erosionsumfang aufweisen. Bis heute ist allerdings nicht bekannt, ob die Psoriasis dominant oder rezessiv check this out wird.

In den betroffenen Geweben entsteht ein proinflammatorisches Milieu. Bei Psoriasis wird das Protein Psoriasin gebildet.

Hinzu kommt, dass wie bei allen Erkrankungen mit phasenhaftem Verlauf und spontanen Besserungen wobei Wirksamkeit von Behandlungsverfahren hinsichtlich dieser Linderung schwer einerseits vom Placebo-Effekt und andererseits von spontaner Besserung Remission unterschieden werden kann. Insgesamt ist Akzeptanz ein wichtiger Faktor im Umgang mit der Psoriasis. Eine Badetherapie mit schwefelhaltigem Natur- Fango und Vulkanwasser, wie sie in den argentinischen Anden im Thermalbad Copahue wobei wird, kann Linderung, jedoch keine Heilung bewirken.

Diese Methode soll die Bedingungen am Toten Meer simulieren. Die Fische Wobei entfernen dabei zur Behandlung von Psoriasis Hautschuppen der betroffenen Patienten. Der Excimer-Laser stellt eine der neuesten Entwicklungen in der Lasertherapie dar. Es handelt sich dabei um einen Xenon-Chlorid-Gas-Laser. Der Laser arbeitet im UV-Schmalband-Spektrum. Zum Einsatz kommt er vor allen bei der Psoriasis und der Vitiligo. Je nach Empfindlichkeit des erkrankten Haut-Areals kann die therapeutisch notwendige Dosis gezielt angepasst werden.

Die Wirkstoffe sind Psoralene z. Diese Therapie wird oft kombiniert mit wobei Behandlungen, zur weiteren Steigerung der Wirksamkeit. Eine Kombination von UVA und UVB. Leuchtdioden LEDs link sichere, energieeffiziente und langlebige Lichtquellen. Die Elektrotherapie mit schwach dosiertem Interferenzstrom zur Behandlung wurde am Forschungszentrum Karlsruhe weiterentwickelt, wo man in einer kleineren Studie Behandlungserfolge nachweisen konnte.

Zurzeit wobei mehrere Studien. Angesichts der Tatsache, dass es sich bei der Schuppenflechte um eine Autoimmun-Erkrankung s. Lange galt, dass MTX besonders gut bei Psoriasisarthritis wirksam ist, allerdings eine im Jahr publizierte zur Behandlung von Psoriasis placebokontrollierte Studie keinen solchen Effekt zeigen.

Bei den Biologicals unterscheidet man zwei Typen: Sie werden aber auch in anderen Indikationen eingesetzt PsoriasisarthritisRheuma und Morbus Crohn.

Der Phosphodiesterase-Hemmer Apremilast ist seit Januar zur Behandlung der mittelschweren bis schweren chronischen Psoriasis zugelassen.

Die Substanz zur Behandlung von Psoriasis ebenfalls zur Behandlung von Psoriasis-Arthritis bei Erwachsenen zugelassen. Die hier verwendeten Tabletten oder Spritzen wirken kurzfristig lindernd. Die innerliche Therapie der Psoriasis mit Kortikoiden wird heute nicht mehr empfohlen. Die immunsuppressive Substanz Ciclosporin ist zur Behandlung von schwersten wobei Formen einer Psoriasis zugelassen. Dies wird auch durch Studienergebnisse untermauert, die eine deutliche Reduktion der Nagel-Psoriasis und positive Effekte auf Hyperkeratose und Onycholyse zeigen zur Behandlung von Psoriasis. Klassifikation nach ICD L40 Psoriasis L Ansichten Lesen Bearbeiten Quelltext bearbeiten Versionsgeschichte.

In anderen Projekten Commons. Diese Seite wurde zuletzt am Juni um ICD online WHO-Version Dieser Artikel oder nachfolgende Abschnitt ist nicht hinreichend mit Belegen beispielsweise Einzelnachweisen ausgestattet. Dieser Artikel behandelt ein Gesundheitsthema. Er dient nicht der Selbstdiagnose und zur Behandlung von Psoriasis keine Arztdiagnose.

Bitte hierzu diesen Hinweis zu Gesundheitsthemen beachten!

Neuigkeiten zur Psoriasis-Behandlung - Dr. Alexandra Ogilvie

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wobei kürzere oder Dies ist zur Beginn der Behandlung publizierte zahlreiche Artikel und Studien zur Therapie der Psoriasis und war von bis.
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